B12 Probiotics

Today I am going to go into greater detail than I have ever done before on why our B12 Probiotics are the best B12 product on the market today.

I’ve always promoted the B12 Probiotics together with the Postbiotics. These two products are my babies lol, and I just always group them together in my promotions.

Generally, I always focus on the Postbiotics during these promotions, because it is literally my favorite gut biotic product in the world, and I truly believe that it is better than any other Probiotic, Prebiotic or other Postbiotics out there. Yet, the demand for the B12 probiotics has always been higher due to how incredible they are at helping people with their B12 levels. People just know without me even having to tell them.

Yes, we are offering both products ‘At-Cost’ today. However, this time we will be focusing more on the B12 Probiotics. 

I truly believe that there is no animal food, product, or supplement that has a more bioavailable B12 within it compared to our B12 Probiotics. As usual just like our other potent one ingredient products, our B12 Probiotics is simply one single ingredient with no other fillers. That one ingredient is P. Freudenreichii, which is simply a probiotic (AKA B12 Probiotics).

In the clinical study <a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657239/” target=”_blank”>here</a>, they talk about how difficult it is to produce a bioavailable active form of B12. The clinical study states, “The complete biosynthesis of cobalamin requires approximately 30 gene products, but it is the final steps of the pathway, namely production, activation and attachment of the lower ligand that decide whether the final product will be an active vitamin B12 or an analog.

In this same clinical study they concluded that these B12 Probiotics produce the active form of B12, “At present, P. freudenreichii (B12 Probiotics) is the only microorganism that has been both granted GRAS status by the FDA, and shown to produce the active form of vitamin B12, making it a unique candidate for the in situ microbial fortification of food products.”

Lastly, this same clinical study states how good it is for fortifying foods with B12 for human food and animal feed preparations, “In recent years the interest in fortification of food products in vitamin B12 by in situ fermentation has been growing. Vitamin B12 production by P. freudenreichii is of special interest because of the Generally Recognized as Safe (GRAS) status of the organism, which allows its direct use in food and feed preparations”

So this clinical study not only proves that these B12 Probiotics are completely active in their bioavailable form, but that they literally use these B12 Probiotics in order to fortify food with B12, and to also feed them to animals, in order to make sure that they get their B12 requirements. 

Then people eat the animal products in order to get that B12. Logic tells me, that if I’m in need of B12, that I should go directly to the B12 Probiotics source that the animals eat.  What kind of breakdown is required in order to get that Vitamin B12 from animal flesh? Many people who eat animal protein and animal products have also been shown to be deficient in B12 quite frequently, and it’s not just Vegans and Vegetarians with B12 deficiencies. These B12 Probiotics could be a great solution. I’m not saying to not eat animal products, but if you are deficient and in need of B12, we need a supplement that works.

This isn’t like getting B12 from a typical B12 Supplement. You are getting it from a living fermented probiotic, making it a Living B12. It is in the Human Active form Hydroxocobalamin. Hydroxocobalamin, is a highly bioavailable form of Vitamin B12, which is generally used to treat people with serious deficiencies.

A chemist who works on the product told me that people don’t need 10,000% of all those B12 products on the market today, as most of that goes right out in the urine. 

What’s even more crazy, for every 1/2 teaspoon serving you take of our B12 Probiotics, you literally get your entire Recommended Dietary Allowance (RDA) of B12, which is 2.4 mcg’s in a living bioavailable form. One jar will last you 35 days taking 1/2 teaspoon, giving you all the B12 you need in a day for over a month (35 days).

When a person has a difficult time absorbing Vitamin B12, doctors generally recommend shots. However, as seen in the clinical studies just below, these B12 probiotics will survive the digestive tract and are the best shot a person has for getting B12 orally.

In the clinical study <a href=”https://www.ncbi.nlm.nih.gov/pubmed/14984773?dopt=Abstract” target=”_blank”>here</a>, and <a href=”https://lait.dairy-journal.org/articles/lait/abs/2002/01/13/13.html” target=”_blank”>here</a>, P. freudenreichii (B12 Probiotics) have shown good constitutional survival under digestive stress and their ability to survive low pH conditions of the stomach and exposure to bile. This gut survival  has been demonstrated in vivo in humans.  High levels of propionibacteria has been detected in feces which provides further proof that it can survive gastrointestinal transit.  Once consumption of the propionibacteria ceased, levels in the feces declined.

Many doctors state that you need intestinal flora in order to absorb B12, and this B12 is an intestinal flora. 

So not only do these B12 Probiotics give you a bioavailable active B12, but it is also extremely beneficial for your gut.

In the clinical study <a href=”https://pubmed.ncbi.nlm.nih.gov/25150945/” target=”_blank”>here</a>, It was shown that the consumption of this bacterium modulates the gut microbiota, which makes P. freudenreichii  both a probiotic and a prebiotic 

In the clinical study <a href=”https://pubmed.ncbi.nlm.nih.gov/16226014/” target=”_blank”>here</a>, P. freudenreichii  was effective in the treatment of mild to moderate ulcerative colitis in a human pilot study. In the study <a href=”https://www.jstage.jst.go.jp/article/bifidus1996/21/2/21_2_115/_article” target=”_blank”>here</a>, P. freudenreichii  relieves constipation in young healthy women.

The reason that I created the Synergy Probiotic Blend, was so that people can take it in conjunction with the B12 Probiotics, due to its Synergistic effect.  Our Synergy Probiotic Blend contains three different Bifidobacterium strains, which as seen in the clinical studies below multiplies by a factor of 10x when taken with P. freudenreichii.

In the clinical study <a href=”https://www.jstage.jst.go.jp/article/bifidus1996/18/1/18_1_27/_pdf” target=”_blank”>here</a>, <a href=”https://pubmed.ncbi.nlm.nih.gov/19847949/” target=”_blank”></a>, <a href=”https://www.jstage.jst.go.jp/article/bifidus1996/18/2/18_2_73/_article” target=”_blank”>here</a>, and <a href=”https://pubmed.ncbi.nlm.nih.gov/10434042/” target=”_blank”>here</a>, shows that P. freudenreichii stimulates the growth of other probiotics including Bifidobacteria in the colon in healthy human subjects, and that Bifidobacterium percentage in the fecal flora and stool frequency were significantly increased by administration of the P. freudenreichii culture. 

There are more clinical studies in the description of the product on our website, that shows it has anti-fungal compounds, anti-viral compounds, protects the intestinal lining, supports absorption of calcium, magnesium, and potassium, supports the synthesis of Vitamin B8 (Biotin), B9 (Folic Acid), binds heavy metals like cadmium and lead and so much more.

This is like the Cadillac of B12 supplements, and it’s great for anyone in need of B12.

P. freudenreichii  was effective in the treatment of mild to moderate ulcerative colitis in a human pilot study (R).

P. freudenreichii  relieves constipation in young healthy women (R).

2) P. freudenreichii  is Anti-inflammatory

A component from P. freudenreichii  suppresses the production of proinflammatory cytokines and attenuates colitis in mice (R).

3) P. freudenreichii  May be Beneficial in IBD

P. freudenreichii  accelerates the healing in rats with colitis (R,R).

A component of P. freudenreichii  improved survival rate and reduced damage in mice with colitis, by attenuating colonic inflammation through balancing intestinal bacterial flora and suppressing lymphocyte infiltration (R).

These two clinical studies show that this probiotic has shown good constitutional survival under digestive stress and their ability to survive low pH conditions of the stomach and exposure to bile. This gut survival  has been demonstrated in vivo in humans.  High levels of propionibacteria has been detected in feces which provides further proof that it can survive gastrointestinal transit.  Once consumption of the dairy propionibacteria ceased, levels in the feces declined.

https://www.ncbi.nlm.nih.gov/pubmed/14984773?dopt=Abstract

https://lait.dairy-journal.org/articles/lait/abs/2002/01/13/13.html

And Here’s just a quick run down of what other clinical studies show it does.

• protect the intestinal lining
• down-regulate NF-κB (nuclear factor-kappa B)
• •which plays a key role in regulating the immune response to infection. Incorrect regulation of this nuclear factor has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory.^{[6][7][8][9][10][11]}
• support absorption of calcium, magnesium and potassium

• production of bacteriocins  13, are similar to yeast and paramecium killing factors
• secretion of anti-fungal compounds  14 
• secretion of anti-viral compounds  15
• synthesis of vitamin B8 (biotin), B9 (folic acid) and B12 (cobalamin)  16  17
• production of trehalose  18 – Propionibacterium freudenreichii produces Trehalose in the colon which has been observed to reduce the level of enterohaemorrhagic Escherichia coli O157:H7.
• inhibition of beta-glucuronidase activities 22,  which is homologous to the Escherichia coli enzyme β-galactosidase.^[12][13] 
• reduction in pathogen adhesion to immobilised mucus  23
• ability to aggregate with pathogenic bacteria  24
• inhibition of Helicobacter pylori adhesion to a human intestinal epithelial cell line  25
• The in vivo experiements with Propionibacterium freudenreichii resulted in modulation of the gastrointestinal microbiota by decereasing Clostridium and Bacteroides.  30

Ohhhh and check this out…

ability to bind to heavy metals

• cadmium  39
• lead  40

https://www.ncbi.nlm.nih.gov/pubmed/18028332?dopt=Abstract

https://www.ncbi.nlm.nih.gov/pubmed/17110980?dopt=Abstract

And lastly, Consumption of propionibacteria is considered safe since it is contained in Emmental cheese which is consumed worldwide.  It is estimated that Emmental cheese contains up to 1,000,000,000 (109) propionibacteria per gram.

In addition to its widespread consumption from Emmental cheese, Propionibacterium freudenreichii has received the “Generally Recognised As Safe” (GRAS) status and has been granted “Qualified presumption of safety” (QPS) status from the European food safety authority.

Lastly, there are no indication of side effects from consuming this product in any of the human trials.

Many doctors state that you need intestinal flora to absorb B12, and this B12 is an intestinal flora…

You simply add water to it and bam, you are done….

This is literally… the best B12 product in the world!